SOCS1 Polyclonal Antibody

Reddot Biotech

SOCS1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

0.89 mg/ml

Unconjugated

Socs1

suppressor of cytokine signaling 1

Cis; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; JA; JAB; JAK2-binding protein; SOC; SOCS-1; SS; SSI-1; STAT-induced STAT inhibitor 1; suppressor of cytokine signaling 1

Rabbit

IgG

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Mouse, Rat

-20°C

12352203