SOCS2 Polyclonal Antibody

Reddot Biotech

SOCS2 Polyclonal Antibody

5

0.4 mg/ml

SOCS2

suppressor of cytokine signaling 2

CIS2; CIS-2; Cish2; cytokine-inducible SH2 protein 2; SOCS-2; SSI2; SSI-2; STATI2; STAT-induced STAT inhibitor 2; suppressor of cytokine signaling 2

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

-20°C

12352203