Western Blot Positive WB detected in: MCF-7 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, U87 whole cell lysate, Rat heart tissue, Rat liver tissue All lanes: SOCS7 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 63, 38 kDa Observed band size: 63 kDa

SOCS7 Antibody

CSB-PA022396LA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA

Product group Antibodies

ReactivityHuman, Rat

TargetSOCS7

Overview

Supplier
Cusabio
Product Name
SOCS7 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID30837
Target name
SOCS7
Target description
suppressor of cytokine signaling 7
Target synonyms
NAP4; NAP-4; Nck, Ash and phospholipase C binding protein; nck, Ash and phospholipase C gamma-binding protein; NCKAP4; NCK-associated protein 4; SOCS-7; suppressor of cytokine signaling 7
Host
Rabbit
Isotype
IgG
Protein IDO14512
Protein Name
Suppressor of cytokine signaling 7
Scientific Description
Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Reactivity
Human, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

SOCS7 Antibody

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Overview