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SOD1 antibody

GTX100659
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSOD1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SOD1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.21 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6647
  • Target name
    SOD1
  • Target description
    superoxide dismutase 1
  • Target synonyms
    ALS, ALS1, HEL-S-44, IPOA, SOD, STAHP, hSod1, homodimer, superoxide dismutase [Cu-Zn], Cu/Zn superoxide dismutase, SOD, soluble, epididymis secretory protein Li 44, indophenoloxidase A, superoxide dismutase 1, soluble, superoxide dismutase, cystolic
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00441
  • Protein Name
    Superoxide dismutase [Cu-Zn]
  • Scientific Description
    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ayoubi R, Alshafie W, You Z, et al. Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence. F1000Res. 2023,12:391. doi: 10.12688/f1000research.132952.2
    Read this paper
  • Ho MH, Yen CH, Hsieh TH, et al. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury. Redox Biol. 2021,46:102067. doi: 10.1016/j.redox.2021.102067
    Read this paper
  • Gentilin E, Cani A, Simoni E, et al. Hydrogen peroxide toxicity on auditory cells: An in vitro study. Chem Biol Interact. 2021,345:109575. doi: 10.1016/j.cbi.2021.109575
    Read this paper
  • Chang HM, Lin HC, Cheng HL, et al. Melatonin Successfully Rescues the Hippocampal Molecular Machinery and Enhances Anti-oxidative Activity Following Early-Life Sleep Deprivation Injury. Antioxidants (Basel). 2021,10(5). doi: 10.3390/antiox10050774
    Read this paper
  • Murata K, Oyama M, Ogata M, et al. Oral administration of Jumihaidokuto inhibits UVB-induced skin damage and prostaglandin E2 production in HR-1 hairless mice. J Nat Med. 2021,75(1):142-155. doi: 10.1007/s11418-020-01465-y
    Read this paper
  • Tsai SH, Hsu LA, Tsai HY, et al. Aldehyde dehydrogenase 2 protects against abdominal aortic aneurysm formation by reducing reactive oxygen species, vascular inflammation, and apoptosis of vascular smooth muscle cells. FASEB J. 2020,34(7):9498-9511. doi: 10.1096/fj.201902550RRR
    Read this paper
  • Liu W, Wu CY, Lu MJ, et al. The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Oxid Med Cell Longev. 2020,2020:5167292. doi: 10.1155/2020/5167292
    Read this paper
  • Chou CK, Huang HW, Yang CF, et al. Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Environ Toxicol. 2019,34(4):401-414. doi: 10.1002/tox.22694
    Read this paper
  • Chang YC, Fong Y, Tsai EM, et al. Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells. Int J Mol Sci. 2018,19(10). doi: 10.3390/ijms19103010
    Read this paper
  • Chen HW, Huang CS, Li CC, et al. Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats. Toxicol Appl Pharmacol. 2014,280(1):1-9. doi: 10.1016/j.taap.2014.07.024
    Read this paper

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