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DCA (Sodium dichloroacetate)

S8615
Selleck Chemicals
Estimated Purity...
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Sodium dichloroacetate (DCA) [2156-56-1]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    DCA (Sodium dichloroacetate), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 microM for PDK2 and PDK4 respectively, has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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