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Chemical Structure
Chemical Structure
Chemical Structure

Sodium salicylate [54-21-7]

Research Use Only
CDX-S0145
Chemodex
CAS Number54-21-7
Product group Chemicals
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Overview

  • Supplier
    Chemodex
  • Product Name
    Sodium salicylate [54-21-7]
  • Delivery Days Customer
    10
  • CAS Number
    54-21-7
  • Certification
    Research Use Only
  • Scientific Description
    Chemical. CAS: 54-21-7. Formula: C7H5O3 . Na. MW: BD9837. Sodium salicylate is a metabolite of aspirin. It is a cell-permeable, non-steroidal anti-inflammatory agent (NSAID) that interferes with TNF-induced NF-kappaB activation by inhibiting phosphorylation and subsequent degradation of the IkappaB-alpha protein. It selectively inhibits TNF-induced activation of p42 (ERK2) and p44 (ERK1) MAP kinases and TNF-induced activation of JNK. It induces apoptosis via p38 kinase activation and inhibits COX-2 and inducible NOS (iNOS) transcription dependent on the experimental setup. It is commonly used for its antipyretic, anti-oxidant, neuroprotective, anti-inflammatory, anti-cancer and analgesic properties. - Sodium salicylate is a metabolite of aspirin. It is a cell-permeable, non-steroidal anti-inflammatory agent (NSAID) that interferes with TNF-induced NF-kappaB activation by inhibiting phosphorylation and subsequent degradation of the IkappaB-alpha protein. It selectively inhibits TNF-induced activation of p42 (ERK2) and p44 (ERK1) MAP kinases and TNF-induced activation of JNK. It induces apoptosis via p38 kinase activation and inhibits COX-2 and inducible NOS (iNOS) transcription dependent on the experimental setup. It is commonly used for its antipyretic, anti-oxidant, neuroprotective, anti-inflammatory, anti-cancer and analgesic properties.
  • Storage Instruction
    RT
  • UNSPSC
    12352200