Sograzepide [155488-25-8]
HY-14850
Overview
- SupplierMedChem Express
- Product NameSograzepide [155488-25-8]
- Delivery Days Customer10
- CAS Number155488-25-8
- CertificationResearch Use Only
- Estimated Purity98.28
- Molecular FormulaC28H30N6O3
- Molecular Weight498.58
- Scientific DescriptionSograzepide (Netazepide; YF 476; YM-220) is an extremely potent, highly selective and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.1 nM, has inhibitory effect on Gastrin/CCK-A activity with an IC50 of 502 nM[1]. Sograzepide (Netazepide; YF 476; YM-220) replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine and cloned human Gastrin/CCK-B receptors, with Ki values of 0.068, 0.62 and 0.19 nM, respectively[2].
- SMILESO=C(NC1=CC=CC(NC)=C1)N[C@H]2C(N(CC(C(C)(C)C)=O)C3=CC=CC=C3C(C4=NC=CC=C4)=N2)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12131703