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Sograzepide [155488-25-8]

HY-14850
MedChem Express
CAS Number155488-25-8
Product group Chemicals
Estimated Purity98.28
Molecular Weight498.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Sograzepide [155488-25-8]
  • Delivery Days Customer
    10
  • CAS Number
    155488-25-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.28
  • Molecular Formula
    C28H30N6O3
  • Molecular Weight
    498.58
  • Scientific Description
    Sograzepide (Netazepide; YF 476; YM-220) is an extremely potent, highly selective and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.1 nM, has inhibitory effect on Gastrin/CCK-A activity with an IC50 of 502 nM[1]. Sograzepide (Netazepide; YF 476; YM-220) replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine and cloned human Gastrin/CCK-B receptors, with Ki values of 0.068, 0.62 and 0.19 nM, respectively[2].
  • SMILES
    O=C(NC1=CC=CC(NC)=C1)N[C@H]2C(N(CC(C(C)(C)C)=O)C3=CC=CC=C3C(C4=NC=CC=C4)=N2)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703

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