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Somatostatin antibody [SOM-018]

Research Use Only
GTX71935
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSST
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Overview

  • Supplier
    GeneTex
  • Product Name
    Somatostatin antibody [SOM-018]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The epitope recognised by this antibody lies within the Somatostatin-14.
  • Application Supplier Note
    Recommended Starting Dilutions:For ICC/IF: Use at a dilution of 1:25-1:100For IHC-Fr: Use at a dilution of 1:25-1:100For IHC-P: Use at a dilution of 1:25-1:100Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SOM-018
  • Concentration
    0.14 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID6750
  • Target name
    SST
  • Target description
    somatostatin
  • Target synonyms
    growth hormone release-inhibiting factor; prepro-somatostatin; SMST; somatostatin; somatostatin-14; somatostatin-28; SST1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP61278
  • Protein Name
    Somatostatin
  • Scientific Description
    The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Neuronal splicing regulator RBFOX3 mediates seizures via regulating Vamp1 expression preferentially in NPY-expressing GABAergic neurons. Huang DF et al., 2022 Aug 16, Proc Natl Acad Sci U S A
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  • A neural substrate of compulsive alcohol use. Domi E et al., 2021 Aug, Sci Adv
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  • TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus. Sato K et al., 2021 Oct 13, J Virol
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  • Molecular Characterization of Superficial Layers of the Presubiculum During Development. Liu J et al., 2021, Front Neuroanat
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  • The Chemokine CXCL14-like Immunoreactivity Co-exists with Somatostatin, but not NPY in the Rat Dorsal Horn and Has Intimate Association with GABAergic Neurons in the Lateral Spinal Nucleus. Yamamoto T et al., 2020 Oct 29, Acta Histochem Cytochem
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  • Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus. Sato M et al., 2020 Jul 7, Cell Rep
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  • Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling. Zhu JW et al., 2020 May 14, Cereb Cortex
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  • Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn. Nelson TS et al., 2019 May 10, Sci Rep
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  • Artemether ameliorates type 2 diabetic kidney disease by increasing mitochondrial pyruvate carrier content in db/db mice. Han P et al., 2019, Am J Transl Res
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  • GABAergic Medial Septal Neurons with Low-Rhythmic Firing Innervating the Dentate Gyrus and Hippocampal Area CA3. Salib M et al., 2019 Jun 5, J Neurosci
    Read more