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ProductsBack/SON antibody

SON antibody

GTX129778
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetSON
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Overview

  • Supplier
    GeneTex
  • Product Name
    SON antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6651
  • Target name
    SON
  • Target description
    SON DNA and RNA binding protein
  • Target synonyms
    BASS1; Bax antagonist selected in Saccharomyces 1; C21orf50; DBP-5; negative regulatory element-binding protein; NRE-binding protein; NREBP; protein SON; SON DNA binding protein; SON3; TOKIMS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP18583
  • Protein Name
    Protein SON
  • Scientific Description
    The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
    Read more
  • Nuclear speckle integrity and function require TAO2 kinase.
    Read more
  • Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway. Aksenova V et al., 2020 Sep 11, Nat Commun
    Read more
  • Influenza virus mRNA trafficking through host nuclear speckles. Mor A et al., 2016 May 27, Nat Microbiol
    Read more