SON antibody
GTX129778
ApplicationsImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSON
Overview
- SupplierGeneTex
- Product NameSON antibody
- Delivery Days Customer9
- Application Supplier NoteICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6651
- Target nameSON
- Target descriptionSON DNA and RNA binding protein
- Target synonymsBASS1; Bax antagonist selected in Saccharomyces 1; C21orf50; DBP-5; negative regulatory element-binding protein; NRE-binding protein; NREBP; protein SON; SON DNA binding protein; SON3; TOKIMS
- HostRabbit
- IsotypeIgG
- Protein IDP18583
- Protein NameProtein SON
- Scientific DescriptionThe protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.Read more
- Nuclear speckle integrity and function require TAO2 kinase.Read more
- Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway. Aksenova V et al., 2020 Sep 11, Nat CommunRead more
- Influenza virus mRNA trafficking through host nuclear speckles. Mor A et al., 2016 May 27, Nat MicrobiolRead more