Sonolisib [502632-66-8]

MedChem Express

Sonolisib [502632-66-8]

5

502632-66-8

98%

C29H35NO8

525.59

Sonolisib (PX-866), an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110alpha), 1.0 nM (p120gamma), 2.9 nM (p110delta)). Antitumor activity.

O=C1C([C@@](CC2)([H])[C@@]3(C)C2=O)=C([C@H](OC(C)=O)C3)[C@]4(C)C(/C(C(O[C@@H]4COC)=O)=C\N(CC=C)CC=C)=C1O

-20°C,-80°C

12352200