Sorafenib-d3

MedChem Express

Sorafenib-d3 [1130115-44-4]

10

1130115-44-4

Research Use Only

99.57

C21H13D3ClF3N4O3

467.84

Sorafenib-d 3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC 50 s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively [1] .

O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NC([2H])([2H])[2H]

-20°C,2°C to 8°C

12352200