Sorafenib (Standard) [284461-73-0]
HY-10201R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameSorafenib (Standard) [284461-73-0]
- Delivery Days Customer5
- CAS Number284461-73-0
- CertificationResearch Use Only
- Molecular FormulaC21H16ClF3N4O3
- Molecular Weight464.83
- Scientific DescriptionSorafenib (Standard) is the analytical standard of Sorafenib. This product is intended for research and analytical applications. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRbeta, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1].
- SMILESO=C(NC(C=C1)=CC=C1OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(Cl)C(C(F)(F)F)=C3
- UNSPSC41116135