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Sorbitol Assay Kit (Colorimetric)

Research Use Only
LS-K165
LifeSpan BioSciences
Product group Assays
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Sorbitol Assay Kit (Colorimetric)
  • Delivery Days Customer
    14
  • Application Supplier Note
    For quantitative determination of D-sorbitol and evaluation of drug effects on sorbitol metabolism.
  • Applications Supplier
    Spectrophotometry (visible) For quantitative determination of D-sorbitol and evaluation of drug effects on sorbitol metabolism.
  • Certification
    Research Use Only
  • Scientific Description
    SORBITOL (glucitol) is a sugar alcohol that is metabolized slowly in the human body. Sorbitol can be obtained from glucose by reducing aldehyde group to a hydroxyl group. Accumulation of excessive sorbitol in erythrocytes, retinal cells, and Schwann cells has been associated with retinopathy, cataracts, peripheral neuropathy and diabetes. Sorbitol is made solely from corn syrup, and found in fruits such as apples, pears, peaches, and prunes. It is widely used as a sugar substitute and as a laxative. It is also utilized in specialty culture media and in healthcare, food and cosmetic products. Sorbitol is measured in biological samples to monitor metabolic pathways and the progression of diabetes. This sorbitol assay involves an end-point enzyme coupled MTT/NAD reaction that forms a colored product with an absorption maximum at 565 nm. The increase in absorbance at 565 nm is directly proportional to the sorbitol concentration.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116133