Sorbitol Dehydrogenase Activity Assay Kit (Colorimetric)
ARG82192
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameSorbitol Dehydrogenase Activity Assay Kit (Colorimetric)
- Delivery Days Customer23
- ApplicationsFunctional Assay
- Assay Detection Range0.1 - 125 U/L
- Assay Sensitivity0.1 U/L
- Assay Time15 min
- CertificationResearch Use Only
- Scientific DescriptionSorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
- Storage Instruction-20°C
- UNSPSC41116133