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ProductsBack/Sort1 Antibody, FITC conjugated

Sort1 Antibody, FITC conjugated

CSB-PA022412LC01RA
Cusabio
ReactivityRat
Product group Antibodies
TargetSort1
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Overview

  • Supplier
    Cusabio
  • Product Name
    Sort1 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID83576
  • Target name
    Sort1
  • Target description
    sortilin 1
  • Target synonyms
    glycoprotein 110; gp110; neurotensin receptor 3; Nt3; NTR3; Nts3; sortilin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO54861
  • Protein Name
    Sortilin
  • Scientific Description
    Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
  • Reactivity
    Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203