SOX2 antibody
GTX101506
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetSOX2
Overview
- SupplierGeneTex
- Product NameSOX2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6657
- Target nameSOX2
- Target descriptionSRY-box transcription factor 2
- Target synonymsANOP3; MCOPS3; sex determining region Y-box 2; SRY (sex determining region Y)-box 2; SRY-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2
- HostRabbit
- IsotypeIgG
- Protein IDP48431
- Protein NameTranscription factor SOX-2
- Scientific DescriptionThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis.Read more
- Hair Cell Generation in Cochlear Culture Models Mediated by Novel gamma-Secretase Inhibitors. Erni ST et al., 2021, Front Cell Dev BiolRead more
- Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth. Yan Z et al., 2021 Feb 19, Cell Death DisRead more
- Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer. Chiu YF et al., 2020 May 19, Sci RepRead more
- Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma. Lee CJ et al., 2018 Dec 3, Sci RepRead more
- Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth. Perez Saturnino A et al., 2018 Nov 9, DevelopmentRead more
- Activating the regenerative potential of Mueller glia cells in a regeneration-deficient retina. Lust K et al., 2018 Jan 29, ElifeRead more
- Notch/Wnt cross-signalling regulates stemness of dental pulp stem cells through expression of neural crest and core pluripotency factors. Uribe-Etxebarria V et al., 2017 Nov 1, Eur Cell MaterRead more
- Neural stem cells induce the formation of their physical niche during organogenesis. Seleit A et al., 2017 Sep 27, ElifeRead more
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![IHC-P analysis of mouse brain tissue using GTX35086 SOX2 antibody [SOX2/1791].](https://www.genetex.com/upload/website/prouct_img/normal/GTX35086/GTX35086_20200115_IHC-P_1638_w_23060801_351.webp)
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