Bio-Connect

SOX2 antibody

GTX101506
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse
TargetSOX2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SOX2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6657
  • Target name
    SOX2
  • Target description
    SRY-box transcription factor 2
  • Target synonyms
    ANOP3; MCOPS3; sex determining region Y-box 2; SRY (sex determining region Y)-box 2; SRY-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP48431
  • Protein Name
    Transcription factor SOX-2
  • Scientific Description
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis.
    Read more
  • Hair Cell Generation in Cochlear Culture Models Mediated by Novel gamma-Secretase Inhibitors. Erni ST et al., 2021, Front Cell Dev Biol
    Read more
  • Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth. Yan Z et al., 2021 Feb 19, Cell Death Dis
    Read more
  • Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer. Chiu YF et al., 2020 May 19, Sci Rep
    Read more
  • Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma. Lee CJ et al., 2018 Dec 3, Sci Rep
    Read more
  • Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth. Perez Saturnino A et al., 2018 Nov 9, Development
    Read more
  • Activating the regenerative potential of Mueller glia cells in a regeneration-deficient retina. Lust K et al., 2018 Jan 29, Elife
    Read more
  • Notch/Wnt cross-signalling regulates stemness of dental pulp stem cells through expression of neural crest and core pluripotency factors. Uribe-Etxebarria V et al., 2017 Nov 1, Eur Cell Mater
    Read more
  • Neural stem cells induce the formation of their physical niche during organogenesis. Seleit A et al., 2017 Sep 27, Elife
    Read more