SP-100030 [154563-54-9]

TargetMol Chemicals

SP-100030 [154563-54-9]

4

154563-54-9

Chemical

Research Use Only

SP-100030

99.57%

C14H5ClF9N3O

437.65

SP-100030 is a dual inhibitor of NF-kappaB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and other T cell lines. Additionally, SP-100030 has been shown to decrease the severity of murine collagen-induced arthritis (CIA).

3 years

C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)(=O)C=2C(C(F)(F)F)=NC(Cl)=NC2

-20°C

12352200