SPDB-DM4
ORB1987730
CAS Number1626359-62-3
Product group Chemicals
Estimated Purity98.00%
Molecular Weight995.59
Overview
- SupplierBiorbyt
- Product NameSPDB-DM4 [1626359-62-3]
- Delivery Days Customer10
- CAS Number1626359-62-3
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC46H63ClN4O14S2
- Molecular Weight995.59
- Scientific DescriptionSPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy.
- SMILES[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C
- Storage Instruction-20°C
- UNSPSC12352200