SPHINX31

MedChem Express

SPHINX31 [1818389-84-2]

10

1818389-84-2

Research Use Only

99.13

C27H24F3N5O2

507.51

SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC 50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF -A 165 a isoform. SPHINX31 can be used to research neovascular eye disease [1] [2] [3] .

O=C(NC1=C(N2CCN(CC3=CC=CC=N3)CC2)C=CC(C(F)(F)F)=C1)C4=CC=C(O4)C5=CC=NC=C5

-20°C,2°C to 8°C

12352200