Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

BPS Bioscience

Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

7

Neutralisation/Blocking

Research Use Only

The SARS-CoV-2 Spike Pseudotyped Lentivirus were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions also contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently measured via luciferase reporter activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.

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