Western Blot Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate All lanes: SPO11 antibody at 5.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45, 41 kDa Observed band size: 45 kDa
Western Blot Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate All lanes: SPO11 antibody at 5.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 45, 41 kDa Observed band size: 45 kDa
SPO11 Antibody
CSB-PA897506LA01HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetSPO11
Overview
- SupplierCusabio
- Product NameSPO11 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23626
- Target nameSPO11
- Target descriptionSPO11 initiator of meiotic double strand breaks
- Target synonymsCT35, SPATA43, TOPOVIA, TOPVIA, meiotic recombination protein SPO11, SPO11 initiator of meiotic double stranded breaks, SPO11 meiotic protein covalently bound to DSB homolog, cancer/testis antigen 35, spermatogenesis associated 43
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5K1
- Protein NameMeiotic recombination protein SPO11
- Scientific DescriptionComponent of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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