SPP-86
E2401
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameSPP-86 [1357349-91-7]
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionSPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinase with an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptoralpha (ERalpha) phosphorylation in MCF7 cells.
- UNSPSC12352200