SPR inhibitor 3 [1292285-54-1]

MedChem Express

SPR inhibitor 3 [1292285-54-1]

9

1292285-54-1

Research Use Only

99.01

C14H18N2O3

262.30

SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 microM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3].

O=C(NCCC1=C(C)NC2=C1C=C(O)C=C2)COC

-20°C

12352200