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SR-4835 [2387704-62-1]

HY-130250
MedChem Express
CAS Number2387704-62-1
Product group Chemicals
Estimated Purity99.82
Molecular Weight499.36
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SR-4835 [2387704-62-1]
  • Delivery Days Customer
    10
  • CAS Number
    2387704-62-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.82
  • Molecular Formula
    C21H20Cl2N10O
  • Molecular Weight
    499.36
  • Scientific Description
    SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death[1].
  • SMILES
    CN1N=CC(N2C3=NC(N4CCOCC4)=NC(NCC5=NC6=C(N5)C=C(Cl)C(Cl)=C6)=C3N=C2)=C1
  • Storage Instruction
    -20°C, 3 years; 4°C, 2 years (Powder)
  • UNSPSC
    12352200

MSDS

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