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WB analysis of HeLa cell lysate using GTX20003 SR-BI antibody.
WB analysis of HeLa cell lysate using GTX20003 SR-BI antibody.
WB analysis of HeLa cell lysate using GTX20003 SR-BI antibody.

SR-BI antibody

Research Use Only
GTX20003
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityBovine, Hamster, Human, Mammals, Mouse, Primate, Rat, Schistosoma japonicum
TargetScarb1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SR-BI antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000 - 1:5000. ICC/IF: 1:50 - 1:1000. IHC-P: 2.5 - 5 microg/ml. FACS: 1:400. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID20778
  • Target name
    Scarb1
  • Target description
    scavenger receptor class B, member 1
  • Target synonyms
    AI120173; CD36; Cd36l; Cd36l1; Chohd; Chohd1; Cla; Cla1; Cla-1; D5Ertd460; D5Ertd460e; HDL QTL 1; Hdlq; Hdlq1; Hlb39; Hlb398; mSR-BI; S; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B1; Sr; Srb1; SR-B1; SRBI; SR-BI
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ61009
  • Protein Name
    Scavenger receptor class B member 1
  • Scientific Description
    Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Plays an important role in the uptake of HDL cholesteryl ester.
  • Reactivity
    Bovine, Hamster, Human, Mammals, Mouse, Primate, Rat, Schistosoma japonicum
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning. Ruhela D et al., 2021 Dec, Brain Behav Immun Health
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  • Binding of liposomes composed of phosphatidylcholine to scavenger receptor class B type 1 and its modulation by phosphatidic acid in HEK293T cells. Koide N et al., 2021 Jun, Biochim Biophys Acta Mol Cell Res
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  • Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein. Stylianou IM et al., 2009 Aug 5, PLoS One
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