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SR1555 (hydrochloride)

HY-120785A
MedChem Express
Molecular Weight496.87
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SR1555 (hydrochloride)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C22H23ClF6N2O2
  • Molecular Weight
    496.87
  • Scientific Description
    SR1555 hydrochloride is the hydrochloride salt form of SR1555 (HY-120785). SR1555 hydrochloride is an inverse agonist for retinoic acid receptor-related orphan nuclear receptor gamma (RORgamma) with an IC50 of 1 microM. SR1555 hydrochloride inhibits the development and function of pro-inflammatory TH17 cell, increases the frequency of anti-inflammatory T regulatory (Treg) cells. SR1555 hydrochloride can be used for research about autoimmune diseases[1].
  • SMILES
    CC(N1CCN(CC2=CC=C(C3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3)C=C2)CC1)=O.Cl
  • UNSPSC
    12352200