SR9186 [1361414-26-7]

MedChem Express

SR9186 [1361414-26-7]

10

1361414-26-7

Research Use Only

98.06

C26H18N6O

430.46

SR9186 (ML368) is a selective CYP3A4 inhibitor with IC50 values of 9, 4, and 38 nM for Midazolam to 1-hydroxymidazolam, Testosterone to 6beta-hydroxytestosterone, and Vincristine to Vincristine M1, respectively. SR-9186 inhibits the development of hepatic-stage P. falciparum and blocks ivermectin metabolism. SR-9186 can be used in breast cancer research[1][2].

O=C(NC1=CC=C(C2=C3C(NC=N3)=NC=C2)C=C1)NC4=CC=C(C5=CC=C(C#N)C=C5)C=C4

-20°C,2°C to 8°C

12352200