SRC3 antibody [N1N2], N-term
GTX113869
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNCOA3
Overview
- SupplierGeneTex
- Product NameSRC3 antibody [N1N2], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8202
- Target nameNCOA3
- Target descriptionnuclear receptor coactivator 3
- Target synonymsACTR; AIB1; AIB-1; amplified in breast cancer 1 protein; bHLHe42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; nuclear receptor coactivator 3; pCIP; RAC3; receptor-associated coactivator 3; SRC3; SRC-3; steroid receptor coactivator protein 3; thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM-1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6Q9
- Protein NameNuclear receptor coactivator 3
- Scientific DescriptionThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells. Liu G et al., 2018 Mar, OncogeneRead more
- Epigenetic Modifications with DZNep, NaBu and SAHA in Luminal and Mesenchymal-like Breast Cancer Subtype Cells. Dagdemir A et al., 2016 Jul-Aug, Cancer Genomics ProteomicsRead more