(S,R,S)-AHPC-C5-COOH [2267282-19-7]

MedChem Express

(S,R,S)-AHPC-C5-COOH [2267282-19-7]

10

2267282-19-7

Research Use Only

98.81

C29H42N4O5S

558.73

(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1alpha interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases[1].

O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NCCCCCCC(O)=O

-20°C,2°C to 8°C

41115800