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(S,R,S)-AHPC-Me hydrochloride [1948273-03-7]

(S,R,S)-AHPC-Me hydrochloride [1948273-03-7]

T13671
TargetMol Chemicals
CAS Number1948273-03-7
Product group Chemicals
Estimated Purity99.18%
Molecular Weight481.05
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (S,R,S)-AHPC-Me hydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    1948273-03-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    (S,R,S)-AHPC-Me hydrochloride
  • Estimated Purity
    99.18%
  • Molecular Formula
    C23H33ClN4O3S
  • Molecular Weight
    481.05
  • Scientific Description
    (S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is utilized in the synthesis of ARV-771, a potent BET protein degrader. It selectively degrades BET protein in castration-resistant cells with a DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, it serves as the VHL ligand from (S,R,S)-AHPC for recruiting von Hippel-Lindau (VHL) protein.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)(C)C)c1ccc(cc1)-c1scnc1C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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