(S,R,S)-AHPC-O-Ph-PEG1-NH2 [2361117-24-8]

MedChem Express

(S,R,S)-AHPC-O-Ph-PEG1-NH2 [2361117-24-8]

12

2361117-24-8

Research Use Only

96.97

C32H41N5O6S

623.76

(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is E3 ligase ligand-linker conjugate and incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-O-Ph-PEG1-NH2 is used in PROTAC EED degrader-1 (HY-130614). PROTAC EED degrader-1 is a PROTAC targeting EED with a pKD of 9.02[1].

NCCOC1=CC=C(C=C1)OCC(N[C@H](C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C=C3)C4=C(N=CS4)C)=O)=O)C(C)(C)C)=O

2°C to 8°C

41115800