(S,R,S)-AHPC-PEG3-N3 [1797406-80-4]

MedChem Express

(S,R,S)-AHPC-PEG3-N3 [1797406-80-4]

10

1797406-80-4

CHEMICAL,general_chemicals_reagents

Research Use Only

99.67

C30H43N7O7S

645.77

(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCN=[N+]=[N-]

-20°C, 3 years; 4°C, 2 years (Powder)

12352005