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SSK1 [2629250-69-5]
T37450
Overview
- SupplierTargetMol Chemicals
- Product NameSSK1 [2629250-69-5]
- Delivery Days Customer4
- CAS Number2629250-69-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameSSK1
- Molecular FormulaC31H34F2N4O18
- Molecular Weight788.61
- Scientific DescriptionSSK1 is a compound that selectively kills senescent cells and is a precursor for beta-galactosidase, which can reduce the inflammatory response of the body. SSK1 can activate the phosphorylation of p38 MAPK and MKK3/MKK6 in senescent cells, and promote mitochondrial DNA damage in senescent cells.
- Shelf life instruction3 years
- SMILES[H][C@]1(O[C@H](CO)[C@@H](O)C1(F)F)n1ccc(NC(=O)OCc2ccc(O[C@@H]3O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)c(c2)[N+]([O-])=O)nc1=O
- Storage Instruction-20°C
- UNSPSC12352200
References
- Yusheng Cai, et al. Elimination of senescent cells by bèta-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice. Cell Res. 2020 Jul;30(7):574-589.Read more