SSR 146977 [264618-44-2]

MedChem Express

SSR 146977 [264618-44-2]

14

264618-44-2

Research Use Only

C35H42Cl2N4O2

621.64

SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM[1].

O=C(N(C)C)NC1(CCN(CC1)CCC[C@]2(CN(CCC2)C(C3=CC=CC=C3)=O)C4=CC=C(C(Cl)=C4)Cl)C5=CC=CC=C5

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