SSR 69071 [344930-95-6]

TargetMol Chemicals

SSR 69071 [344930-95-6]

44

344930-95-6

Research Use Only

SSR 69071

C27H32N4O7S

556.63

SSR69071 is a potent, orally active, and selective inhibitor of neutrophil elastase, displaying higher affinity for human elastase (Ki = 0.0168 nM) compared to rat (Ki = 3 nM), mouse (Ki = 1.8 nM), and rabbit (Ki = 58 nM) elastases [2]. It reduces myocardial infarct size following ischemia-reperfusion injury [1] and has potential for treating chronic obstructive pulmonary diseases, asthma, emphysema, cystic fibrosis, and various inflammatory diseases.

3 years

C(C)(C)C1=C2C(S(=O)(=O)N(COC=3N=C4N(C(=O)C3)C=CC=C4OCCN5CCCCC5)C2=O)=CC(OC)=C1

-20°C

12352200