Western blot analysis of extracts of various cell lines using SSRP1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using SSRP1 Polyclonal Antibody at dilution of 1:1000.
SSRP1 Polyclonal Antibody
E-AB-61945
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSSRP1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
- UNSPSC12352203