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ProductsBack/SSTR2 Antibody, Biotin conjugated

SSTR2 Antibody, Biotin conjugated

CSB-PA022725LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetSSTR2
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Overview

  • Supplier
    Cusabio
  • Product Name
    SSTR2 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID6752
  • Target name
    SSTR2
  • Target description
    somatostatin receptor 2
  • Target synonyms
    somatostatin receptor type 2; SRIF-1; SS2R
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP30874
  • Protein Name
    Somatostatin receptor type 2
  • Scientific Description
    Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203