Western Blot Positive WB detected in: Mouse spleen tissue All lanes: SSTR2 antibody at 2.7ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 42, 41 kDa Observed band size: 42 kDa

SSTR2 Antibody

Name: SSTR2 Antibody
SKU: CSB-PA022725LA01HU_C90
Availability: BackOrder

CSB-PA022725LA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetSSTR2

Overview

Supplier
Cusabio
Product Name
SSTR2 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID6752
Target name
SSTR2
Target description
somatostatin receptor 2
Target synonyms
somatostatin receptor type 2; SRIF-1; SS2R
Host
Rabbit
Isotype
IgG
Protein IDP30874
Protein Name
Somatostatin receptor type 2
Scientific Description
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

SSTR2 Antibody

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Overview

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