WB analysis of K562 (A), human spleen (B) whole cell lysates using GTX55282 ST5 antibody.
WB analysis of K562 (A), human spleen (B) whole cell lysates using GTX55282 ST5 antibody.
ST5 antibody
GTX55282
Overview
- SupplierGeneTex
- Product NameST5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6764
- Target nameDENND2B
- Target descriptionDENN domain containing 2B
- Target synonymsDENN domain-containing protein 2B; DENN/MADD domain containing 2B; heLa tumor suppression 1; HTS1; p126; ST5; suppression of tumorigenicity 5 protein
- HostRabbit
- IsotypeIgG
- Protein IDP78524
- Protein NameSuppression of tumorigenicity 5 protein
- Scientific DescriptionThis gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis. Kumar R et al., 2022 Feb 25, Sci AdvRead more