STA-2842 [1046490-67-8]
HY-117051
CAS Number1046490-67-8
Product group Chemicals
Molecular Weight550.65
Overview
- SupplierMedChem Express
- Product NameSTA-2842 [1046490-67-8]
- Delivery Days Customer5
- CAS Number1046490-67-8
- CertificationResearch Use Only
- Molecular FormulaC29H38N6O5
- Molecular Weight550.65
- Scientific DescriptionSTA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
- SMILESO=C(C1=NN=C(N1C2=CC=C(CN3CCOCC3)C=C2)C4=C(O)C=C(O)C(C(C)C)=C4)NCCN5CCOCC5
- UNSPSC12352200