Western blot All lanes: STAMBP antibody at 12microg/ml Lane 1: Jurkat whole cell lysate Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 40 kDa Observed band size: 49 kDa
Western blot All lanes: STAMBP antibody at 12microg/ml Lane 1: Jurkat whole cell lysate Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 40 kDa Observed band size: 49 kDa
STAMBP Antibody
CSB-PA022794HA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTAMBP
Overview
- SupplierCusabio
- Product NameSTAMBP Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10617
- Target nameSTAMBP
- Target descriptionSTAM binding protein
- Target synonymsAMSH, MICCAP, STAM-binding protein, associated molecule with the SH3 domain of STAM, endosome-associated ubiquitin isopeptidase, testicular secretory protein Li 54
- HostRabbit
- IsotypeIgG
- Protein IDO95630
- Protein NameSTAM-binding protein
- Scientific DescriptionZinc metalloprotease that specifically cleaves Lys-63-linked polyubiquitin chains. Does not cleave Lys-48-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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