Stanniocalcin 1 antibody
GTX129092
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSTC1
Overview
- SupplierGeneTex
- Product NameStanniocalcin 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.26 mg/ml
- ConjugateUnconjugated
- Gene ID6781
- Target nameSTC1
- Target descriptionstanniocalcin 1
- Target synonymsstanniocalcin-1; STC
- HostRabbit
- IsotypeIgG
- Protein IDP52823
- Protein NameStanniocalcin-1
- Scientific DescriptionThis gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5 UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Targeting stanniocalcin-1-expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer. Abe K et al., 2021 May, Cancer MedRead more
- Epithelial expression and role of secreted STC1 on asthma airway hyperresponsiveness through calcium channel modulation. Xu J et al., 2021 Aug, AllergyRead more