Stanniocalcin 2 antibody
GTX82231
Overview
- SupplierGeneTex
- Product NameStanniocalcin 2 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8614
- Target nameSTC2
- Target descriptionstanniocalcin 2
- Target synonymsstanniocalcin-2; stanniocalcin-related protein; STC-2; STC-related protein; STCRP
- HostChicken
- IsotypeIgY
- Protein IDO76061
- Protein NameStanniocalcin-2
- Scientific DescriptionHas an anti-hypocalcemic action on calcium and phosphate homeostasis. This protein is a secreted. homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport. cell metabolism. or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction. reduced bone and skeletal muscle growth. and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
- ReactivityGoat, Human
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Exploration of the lactation function of protein phosphorylation sites in goat mammary tissues by phosphoproteome analysis. Zhu C et al., 2021 Sep 28, BMC GenomicsRead more
- MiR-184 Combined with STC2 Promotes Endometrial Epithelial Cell Apoptosis in Dairy Goats via RAS/RAF/MEK/ERK Pathway. Cui J et al., 2020 Sep 7, Genes (Basel)Read more
- CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells. Zhu C et al., 2020 Aug 4, Animals (Basel)Read more