
IHC-P analysis of human colon carcinoma tissue using GTX64344 STAT1 antibody. Dilution : 1:100
STAT1 antibody
GTX64344
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTAT1
Overview
- SupplierGeneTex
- Product NameSTAT1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:20 - 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6772
- Target nameSTAT1
- Target descriptionsignal transducer and activator of transcription 1
- Target synonymsCANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, transcription factor ISGF-3 components p91/p84
- HostRabbit
- IsotypeIgG
- Protein IDP42224
- Protein NameSignal transducer and activator of transcription 1-alpha/beta
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang Y, Zhu S, Wei W, et al. Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice. Aging (Albany NY). 2020,12(20):20184-20197. doi: 10.18632/aging.103749Read this paper
- Gong W, Qie S, Huang P, et al. Deletion of long noncoding RNA EFNA3 aggravates hypoxia-induced injury in PC-12 cells by upregulation of miR-101a. J Cell Biochem. 2019,120(1):836-847. doi: 10.1002/jcb.27444Read this paper











![WB analysis of human malignant melanoma cells (short-term culture derived from a patient) treated with IFN-gamma (10 ng/ml) and IFN-alpha (1000 IU/ml and 5000 IU/ml) using GTX23987 STAT1 antibody [SM1]. Upper Lane : GTX23991 STAT1 (phospho Ser727) antibody [PSM1] Lower Lane : GTX23987 STAT1 antibody [SM1]](https://www.genetex.com/upload/website/prouct_img/normal/GTX23987/GTX23987_20191025_AP_001_184_w_23060722_761.webp)