
WB analysis of extracts from HeLa cells treated with IFNa or calf intestinal phosphatase (CIP) using GTX50118 STAT1 (phospho Tyr701) antibody.
STAT1 (phospho Tyr701) antibody
GTX50118
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSTAT1
Overview
- SupplierGeneTex
- Product NameSTAT1 (phospho Tyr701) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6772
- Target nameSTAT1
- Target descriptionsignal transducer and activator of transcription 1
- Target synonymsCANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, transcription factor ISGF-3 components p91/p84
- HostRabbit
- IsotypeIgG
- Protein IDP42224
- Protein NameSignal transducer and activator of transcription 1-alpha/beta
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kanazawa N, Hemmi H, Kinjo N, et al. Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency. Nat Commun. 2021,12(1):6819. doi: 10.1038/s41467-021-27085-yRead this paper
- Chang JT, Yang CS, Chen YS, et al. Genome and infection characteristics of human parechovirus type 1: the interplay between viral infection and type I interferon antiviral system. PLoS One. 2015,10(2):e0116158. doi: 10.1371/journal.pone.0116158Read this paper










![WB analysis of human malignant melanoma cells (short-term culture derived from a patient) treated with IFN-gamma (10 ng/ml) and IFN-alpha (1000 IU/ml and 5000 IU/ml) using GTX23987 STAT1 antibody [SM1]. Upper Lane : GTX23991 STAT1 (phospho Ser727) antibody [PSM1] Lower Lane : GTX23987 STAT1 antibody [SM1]](https://www.genetex.com/upload/website/prouct_img/normal/GTX23987/GTX23987_20191025_AP_001_184_w_23060722_761.webp)