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ProductsBack/STAT3-IN-13 [2248552-86-3]
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STAT3-IN-13 [2248552-86-3]

Research Use Only
T62491
TargetMol Chemicals
Molecular Weight436.49
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    STAT3-IN-13 [2248552-86-3]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    STAT3-IN-13
  • Molecular Formula
    C21H20N6O3S
  • Molecular Weight
    436.49
  • Scientific Description
    STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which induces apoptosis and inhibits tumor cell growth and metastasis.STAT3-IN-13 can be used to study breast cancer and liver cancer. The study of breast cancer and hepatocellular carcinoma.
  • Shelf life instruction
    3 years
  • SMILES
    C(#N)C=1C2=C(SC1NC(=O)C=3C=NN(C)C3)CN(C(NC4=CC=C(OC)C=C4)=O)CC2
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Jin W, et al. Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and Metastasis. J Med Chem. 2022 May 12;65(9):6710-6728.
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