STAT3-IN-38

MedChem Express

STAT3-IN-38

5

Research Use Only

C35H45NO3S

559.80

STAT3-IN-38 (Compound 4m) is an inhibitor of STAT3 (KD of rhSTAT3: 45.33 microM). STAT3-IN-38 binds to the SH2 domain of STAT3 protein and suppresses the STAT3s phosphorylation at site pTyr705 as well as its downstream genes (Survivin and Mcl-1). STAT3-IN-38 could block cell-cycle and induce Apoptosis in colorectal cancer cells[1].

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12352200