STAT4 (phospho Tyr693) antibody

GeneTex

STAT4 (phospho Tyr693) antibody - Orthogonal Validated

9

WB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

STAT4

signal transducer and activator of transcription 4

signal transducer and activator of transcription 4; signal transducer and activator of transcription 4 variant 3; SLEB11

Rabbit

IgG

Signal transducer and activator of transcription 4

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203