Western blot analysis of extracts of NCI-H460 cells using STAT4 Polyclonal Antibody at dilution of 1:1000.
STAT4 Polyclonal Antibody
E-AB-61450
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSTAT4 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
- UNSPSC12352203