STAT4 Polyclonal Antibody

Reddot Biotech

STAT4 Polyclonal Antibody

5

1.2 mg/ml

STAT4

signal transducer and activator of transcription 4

signal transducer and activator of transcription 4; signal transducer and activator of transcription 4 variant 3; SLEB11

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

-20°C

12352203